Monthly Archives: October 2010

The Art and Science of Recrystallization

Recrystallization as a means of purifying organic compounds is a time honored method. Long before Ultra High Performance Liquid Chromatography and Supercritical Fluid Chromatography there was recrystallization. Of course, recrystallization is directly related to solubilities. The science of recrystallization is that a compound may be appreciably more soluble in a hot solvent than a cold […]

The role of scientific articles in OChem laboratories: Part I

Organic chemistry lab seems to be an appropriate place to read scientific articles to plan an experiment or to relate an experiment to a formal scientific research project. Almost all labs performed in organic chemistry have their roots in a formal scientific article. However, the seminal article may be quite old! For example, Fischer esterification […]

The Liquid-Liquid Shell Game

In the classic shell game, an object is placed under one of three shells and the shells are skillfully manipulated until it is not clear to anyone but the instigator under which shell the object resides. In the liquid-liquid shell game a mixture of two compounds is dissolved in ether and extracted with three different […]