Monthly Archives: October 2013

Benz But Doesn’t Break. Part VI

I reported earlier that our attempts to run the thiamine catalyzed 4-methoxybenzaldehyde (anisaldehyde) coupling to 4,4’-dimethoxybenzoin (anisoin) did not appear to generate any products. I ended up pouring all the student prepared reaction mixtures into a 1 L Erlenmeyer flask and let it sit in my research lab. One day towards the end of August […]

Benz But Doesn’t Break. Part V

The third step of the modified benzilic acid synthesis project proceeded well under the same conditions as the benzil to benzilic acid rearrangement as outlined in a previous post. The products were characterized by melting point, UV absorption, IR, 1H and 13C NMR. The carboxylic acid products were not compatible with the GC column we […]